Following is a list of malignant spindle cell tumors. On the other end of the spectrum, neither the nuclear nor the cytoplasmic features help in distinguishing high-grade tumors. The presence of atypical mitotic figures is a very useful feature in cytodiagnosis. The diagnosis of malignancy is based on the cellularity and the presence of single cells, and the cytological features of malignancy, namely, hyperchromasia in almost all the cells. The role of cytology in malignant spindle cell tumors is to initially diagnose them as malignant spindle cells and subsequently, to subtype them. Hence, the diagnosis of a spindle cell tumor should follow after careful exclusion of benign lesions. Available from: Ĭytological diagnosis of spindle cell tumors is fraught with the greatest diagnostic difficulty and the greatest potential for false positive and false negative diagnoses compared to other soft tissue tumors due to the difficulty in distinguishing benign and low-grade tumors. Cytology of soft tissue tumors: Malignant spindle cell tumors. Cytology of soft tissue tumors: Malignant spindle cell tumorsĭepartment of Pathology, Nizam's Institute of Medical Sciences, Punjagutta, Hyderabad - 500 082, IndiaĬlick here for correspondence address and email
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